| Event | Mark | Athlete | Year Achieved |
| 100m | 11.00 | Deajah Stevens (Benjamin Cardozo) | 2017 |
| 200m | 22.09 | Deajah Stevens (Benjamin Cardozo) | 2017 |
| 300m | 36.51 | Natasha Hastings (AP Randolph) | 2020 |
| 400m | 49.61 | Phyllis Francis (McCauley) | 2019 |
| 600m | 1:26.00 | Meredith Rainey (St. Ann's) | 1992 |
| 800m | 1:57.04 | Meredith Rainey (St. Ann's) | 1996 |
| 1000m | 2:37.02 | Diana Richburg (Lansingburgh) | 1988 |
| 1500m | 4:01.79 | Diana Richburg (Lansingburgh) | 1987 |
| Mile | 4:25.77 | Diana Richburg (Lansingburgh) | 1987 |
| 2000m | 5:46.12 | Suzanne Girard (Maine-Endwell) | 1986 |
| 3000m | 8:35.03 | Jen Rhines (Liverpool) | 2007 |
| 2 Miles | 9:42.99 | Nnenna Lynch (Hunter HS) | 1998 |
| 5000m | 14:42.64 | Molly Huddle (Notre Dame Elmira) | 2014 |
| 10,000m | 30:13.17 | Molly Huddle (Notre Dame Elmira) | 2016 |
| Half-Marathon | 67.25 | Molly Huddle (Notre Dame Elmira) | 2018 |
| Marathon | 2:26.33 | Molly Huddle (Notre Dame Elmira) | 2019 |
| Hurdles | | | |
| 110HH | 12.8 | Monifa Taylor (Truman) | 1992 |
| 400H | 52.16 | Dalilah Muhamad (Benjamin Cardozo) | 2019 |
| 3000m Steeple | 9:43.37 | Megan Patrigenelli (Monroe-Woodbury) | 2016 |
| Field | | | |
| LJ | 21-11 | Lanae Tava-Thomas (Rush-Henrietta) | 2017 |
| TJ | 45-11.25 | Marie-Jose Ebwea-Bile (Benjamin Cardozo) | 2018 |
| HJ | 6-2.25 | Stacy Ann Grant (South Shore) | 2003 |
| 6-2.25 | Kaitlin Whitehorn (John Glenn) | 2016 |
| 6-8.25 | Brigetta Barrett (RF Ketchum - Soph Only) | 2013 |
| PV | 16-2 | Jenn Suhr (Fredonia) | 2018 |
| SP | 55-2.5 | Brittany Pryor (Niagara Falls) | 2007 |
| DT | 200-9 | Summer Pierson (Niskayuna) | 2009 |
| HT | 231-8 | Dawn Ellerbe (Central Islip) | 2001 |
| Jav | 189-4 | Jeanne Villegas (JFK Catholic) | 1987 |
| Hept | 5784 | Heidi Mann (Queensbury) | 1987 |